This site is focused on:-

1) The Fluids of the Inner Ear, perilymph and endolymph

2) The Barriers of the Ear, controlling how substances enter and leave the ear

3) Local Drug Delivery to the Inner Ear

4) Computer Simulations of Drug Distribution in the Ear

Iillustrations at the top are:

(Left) A guinea pig inner ear in which the perilymphatic spaces were filled with orange latex and the endolymph with dark blue latex, then dissected open. Back in the 1980's, this was our first 3D view of the inner ear fluid spaces.

(Middle) Digital 3D reconstruction of the fluid spaces of the guinea pig ear. Yellow:scala tympani; Green: scala vestibuli; Blue:endolymph; Cyan: round window; Brown: stapes.

(Right) A mid-modiolar histologic section through the guinea pig ear showing the membranous and cellular structures inside.


Now Available

   FluidSim 4.03

A completely new version of our Cochlear Fluids Simulation Program

Available Here

 This website has been personally-generated by Alec Salt and is not affiliated with or supported by Washington University.