The field of drug delivery to the inner ear is still very young. There are many complex aspects, including serious measurement artifacts that can distort drug measurements from animals. Most locally-applied drugs do not disperse evenly throughout the ear and gradients of distribution are common. As a result, quantitative interpretation of perilymph or tissue drug measurements typically requires some form of computer modelling. Nothing is worse for the field than to have people collecting data at great expense that are distorted or uninterpretable (see our page on the "Serial Barriers" problem). This can lead to bad decisions based on flawed data or incorrect interpretation. There are many instances where this has already happened. Many of the pitfalls can be avoided if the studies are carefully planned.
We are therefore happy to provide guidance and advice to people at all stages of the drug-delivery-to-the-inner-ear pipeline. This covers a wide range of issues from the design of PK studies in animals to the protocol specification used to deliver drugs to the ear in the clinic. We want to make sure that measurements are valid, that they are interpreted correctly and that the resulting delivery to humans is fully optimized for success. It is terrible for the field when someone has a well-designed therapy in-hand which proves to be ineffective in humans because it wasn't delivered properly.
We don't need to have a contract in place to hold initial discussions. After that, it depends how much help you want or need from us.